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92 In this mechanism, bacterial GSH is an essential cofactor, and mutants that are defective in GSH biosynthesis cannot inactivate fosfomycin, even though they possess the resistance gene

Circulation 106: 25032509

Consider that ethanol upregulates CYP enzymes, which will increase the metabolism of acetaminophen, leading to a shorter duration of action and increased production of the toxic metabolite NAPQI

Systematic review registration: CRD42025644894

Plantz BA, Sinha J, Villarete L, Nickerson KW, Schlegel VL (2006) Pichia pastoris fermentation optimization: energy state and testing a growth-associated model